Our Idiot Brother
Jeremy: [Referring to Ned not being able to go through with a 3-way with a man and a woman] Just because you’re straight doesn’t mean you’re homophobic.
Ned: [Feeling ashamed of himself] I don’t know, maybe I should have tried harder.
Good enough. Though it definitely could’ve been funnier, or even in the other direction, more dramatic, where Ned is this kook in a super serious world, instead of just being a lallygagging over-trusting fool in a world full of cynics. Funniest thing about the movie, though? T.J. Miller’s (fake) Beard:

Denver! Yeah!